INCRETIN-BASED THERAPY
نویسندگان
چکیده
منابع مشابه
Incretin-based Therapy in the Management of Type 2 Diabetes
Type 2 diabetes is a progressive disease due to reduced beta cell mass, which results in the failure of traditional treatment and the need for more intensive therapeutical measures to maintain a good glycaemic control. Within the last decade there was a preoccupation for developing new classes of drugs to achieve several goals: glycaemic control, weight loss and to preserve residual beta cell m...
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Type 2 diabetes mellitus (T2DM) is widely prevalent and a critical risk factor for cardiovascular disease that increases both morbidity and mortality. Recently, new therapies based on the actions of the incretin hormones have become widely used, offering advantages over conventional treatments by limiting hypoglycemia and achieving glycemic control. Moreover, many experimental studies have sugg...
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Diabetic vascular complications are the most common cause of mortality and morbidity worldwide, with numbers of affected individuals steadily increasing. Diabetic vascular complications can be divided into two categories: macrovascular andmicrovascular complications. Macrovascular complications include coronary artery diseaseand cerebrovascular disease, while microvascular complications include...
متن کاملIntegrating incretin-based therapy into type 2 diabetes management.
LEARNING OBJECTIVES 1. Explain the concept of the incretin effect and describe defects in incretin secretion and incretin action that occur in type 2 diabetes mellitus (T2DM) 2. Provide an overview of the rationale and role of incretin-based therapy as described in current practice guidelines for the management of patients with T2DM 3. Compare the efficacy, safety, and tolerability of the incre...
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Incretin-based therapies have established a foothold in the diabetes armamentarium through the introduction of oral dipeptidyl peptidase-4 inhibitors and the injectable class, the glucagon-like peptide-1 receptor agonists. In 2009, the American Diabetes Association and European Association for the Study of Diabetes authored a revised consensus algorithm for the initiation and adjustment of ther...
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ژورنال
عنوان ژورنال: Juntendo Medical Journal
سال: 2012
ISSN: 0022-6769,2188-2134
DOI: 10.14789/pjmj.58.490